Isaac, 2686 presbyter of the church at Antioch, whose many works cover a long period, wrote in Syriac especially against the Nestorians and Eutychians. He lamented the downfall of Antioch in an elegiac poem, taking up the same strain that Ephraim, the deacon, sounded on the downfall of Nicomedia. He died during the reign of Leo and Majorianus.
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